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George Kittle (knee) remains out for 49ers

San Francisco 49ers tight end George Kittle (knee) remained sidelined on Thursday.

What It Means:

Kittle isn't expected to play Week 11 against the Arizona Cardinals on Sunday. Emmanuel Sanders (ribs) has also been sidelined at practice this week, so Deebo Samuel could be the 49ers' top target against the second-worst pass defense in the NFL. Ross Dwelley, Kittle's backup, caught 3 passes on 7 targets for 24 yards in Week 10 with Kittle sidelined.

Kittle is averaging 11.4 FanDuel points per game this season. He has 46 catches on 57 targets for 541 yards and 2 touchdowns in eight games.